My research aims to interrogate the structure and function of the cortical column as it varies across sensory systems in order to map noninvasive biomarkers of functional areas and to study the mechanisms of plasticity.

The Miller Lab uses an integrative strategy that combines measurements from multiple scales of organization to investigate the evolution and plasticity of the fundamental building block of the mammalian cerebral cortex, the cortical column. We leverage advanced computational methods to integrate measurements of brain structure and function from the level of single-cell genomics and deep-learning morphometrics through single-unit receptive field mapping to macroscale parcellation and tractography using ultra high field (9.4T, 7T) magnetic resonance imaging (MRI) to create multidimensional maps of the brain. We are interested in understanding the fundamental organization of the cerebral cortex as a laminated aspect of the mammalian brain in order to develop and validate the biomarkers of neurophysiological organization that are needed to identify diseased from healthy tissue, and to map evolutionary processes over time.