Ko Laboratory

Lab Group PhotoThank you for visiting the Ko Laboratory page, a place for junior scientists who have a passion for science. This is their laboratory to achieve their goals for learning scientific skills, experimenting with new ideas, growing to excellency, and developing new knowledge for all. These goals are achieved by working on a few projects.

One of the main themes of the laboratory is to elucidate the mechanism governing the breakdown and rupture of the follicle during the ovulatory process. This process is activated by a surge of luteinizing hormone (LH), a pituitary gonadotropin, which triggers dramatic changes in the ovary at molecular, biochemical, and physical levels, eventually leading to the rupture of a mature follicle, releasing an egg. However, many of the key factors involved in and the mechanism governing the process of LH release and follicle rupture are yet to be unveiled.

Our research team aims to reveal the LH-induced intraovarian molecular events and the roles that ovarian steroid hormones play in this process, ultimately to help women who suffer from infertility caused by ovulatory defects. Other exciting projects include reproductive toxicology, novel roles that sex steroids play in reproductive/non-reproductive tissues and generation of novel transgenic animals and databases for shared uses.

Please take a moment to explore our projects in the tabs below or see some funny or serious photos taken by our team members in the gallery below.

Our Principal Investigator is CheMyong Ko.

Please contact any of our team members if you are interested in our projects or want to collaborate with us. You can find their email contacts and projects at our website here.

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