Additional Campus Affiliations
Assistant Professor, Molecular and Integrative Physiology
Recent Publications
Schappe, M. S., Brinn, P. A., Joshi, N. R., Greenberg, R. S., Min, S., Alabi, A. R. A., Zhang, C., & Liberles, S. D. (2024). A vagal reflex evoked by airway closure. Nature, 627(8005), 830-838. https://doi.org/10.1038/s41586-024-07144-2
Schappe, M. S., Stremska, M. E., Busey, G. W., Downs, T. K., Seegren, P. V., Mendu, S. K., Flegal, Z., Doyle, C. A., Stipes, E. J., & Desai, B. N. (2022). Efferocytosis requires periphagosomal Ca2+-signaling and TRPM7-mediated electrical activity. Nature communications, 13(1), Article 3230. https://doi.org/10.1038/s41467-022-30959-4
Mendu, S. K., Stremska, M. E., Schappe, M. S., Moser, E. K., Krupa, J. K., Rogers, J. S., Stipes, E. J., Parker, C. A., Braciale, T. J., Perry, J. S. A., & Desai, B. N. (2020). Targeting the ion channel TRPM7 promotes the thymic development of regulatory T cells by promoting IL-2 signaling. Science Signaling, 13(661), Article eabb0619. https://doi.org/10.1126/scisignal.abb0619
Chiu, Y. H., Schappe, M. S., Desai, B. N., & Bayliss, D. A. (2018). Revisiting multimodal activation and channel properties of Pannexin 1. Journal of General Physiology, 150(1), 19-39. https://doi.org/10.1085/jgp.201711888
Schappe, M. S., Szteyn, K., Stremska, M. E., Mendu, S. K., Downs, T. K., Seegren, P. V., Mahoney, M. A., Dixit, S., Krupa, J. K., Stipes, E. J., Rogers, J. S., Adamson, S. E., Leitinger, N., & Desai, B. N. (2018). Chanzyme TRPM7 Mediates the Ca2+ Influx Essential for Lipopolysaccharide-Induced Toll-Like Receptor 4 Endocytosis and Macrophage Activation. Immunity, 48(1), 59-74.e5. https://doi.org/10.1016/j.immuni.2017.11.026