Abstract Background: A core cognitive attribute of depression is lower specificity in the expression of autobiographical memories. Despite interventions targeting memory specificity in depression, its underlying mechanisms are not yet fully understood. Depression also relates to poorer memory for episodic details; here we examine whether reduced specificity might simply...

Abstract Signal detection theory (SDT; Tanner & Swets in Psychological Review 61:401-409, 1954) is a dominant modeling framework used for evaluating the accuracy of diagnostic systems that seek to distinguish signal from noise in psychology. Although the use of response time data in psychometric models has increased in recent years, the incorporation of response time data into SDT models...

Abstract Written memoranda of conversations, or memcons, provide a near-contemporaneous record of what was said in conversation, and offer important insights into the activities of high-profile individuals. We assess the impact of writing a memcon on memory for conversation. Pairs of participants engaged in conversation and were asked to recall the contents of that conversation 1 week later. One...

Abstract The mechanisms underlying a tendency among individuals with depression to report personal episodic memories with low specificity remain to be understood. We assessed a sample of undergraduate students with dysphoria to determine whether depression relates to a broader dysregulation of balancing accuracy and informativeness during memory reports. Specifically, we investigated...

Abstract After a crime is committed, investigators may query witnesses about whether they believe they will be to identify the perpetrator. However, we know little about how such metacognitive judgments are related to performance on a subsequent lineup identification task. The extant research has found the strength of this relationship to be small or nonexistent, which conflicts with the large...

Abstract Prior familiarity with a face seems to substantively change the way we encode and recognize later instances of that face. We report five experiments that examine the effects of varying levels of prior familiarity and conceptual knowledge on face recognition memory. All experiments employed a 3-phase procedure, in which faces were familiarized in varying ways and to varying extents prior...

Abstract Remarkable progress in bioengineering over the past two decades has enabled the formulation of fundamental design principles for a variety of medical and non-medical applications. These advancements have laid the foundation for building multicellular engineered living systems (M-CELS) from biological parts, forming functional modules integrated into living machines. These cognizant...

Abstract Bioengineering approaches that combine living cellular components with three-dimensional scaffolds to generate motion can be used to develop a new generation of miniature robots. Integrating on-board electronics and remote control in these biological machines will enable various applications across engineering, biology, and medicine. Here, we present hybrid bioelectronic robots equipped...

Abstract Fragile X (FX) syndrome is one of the leading inherited causes of autism spectrum disorder (ASD). A majority of FX and ASD patients exhibit sensory hypersensitivity, including auditory hypersensitivity or hyperacusis, a condition in which everyday sounds are perceived as much louder than normal. Auditory processing deficits in FX and ASD also afford the opportunity to develop objective...

Abstract Listening in noisy or complex sound environments is difficult for individuals with normal hearing and can be a debilitating impairment for those with hearing loss. Extracting meaningful information from a complex acoustic environment requires the ability to accurately encode specific sound features under highly variable listening conditions and segregate distinct sound streams from...