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Uwe Rudolph

Professor, Comparative Biosciences
Research: Neurobiology of Cognitive Function in Aging and Pathophysiology of Neuropsychiatric Disorders

Additional Campus Affiliations

Head, Comparative Biosciences
Professor, Comparative Biosciences
Affiliate, Carl R. Woese Institute for Genomic Biology

Recent Publications

Kambali, M., Li, Y., Unichenko, P., Feria Pliego, J. A., Yadav, R., Liu, J., McGuinness, P., Cobb, J. G., Wang, M., Nagarajan, R., Lyu, J., Vongsouthi, V., Jackson, C. J., Engin, E., Coyle, J. T., Shin, J., Hodgson, N. W., Hensch, T. K., Talkowski, M. E., ... Rudolph, U. (Accepted/In press). An increased copy number of glycine decarboxylase (GLDC) associated with psychosis reduces extracellular glycine and impairs NMDA receptor function. Molecular Psychiatry. https://doi.org/10.1038/s41380-024-02711-5

Ko, C. J., Rudolph, U., & Constable, P. (2024). A Novel, Humane Method of Sterilizing Dogs, Cats, and Pigs. American journal of veterinary research, 85(11). https://doi.org/10.2460/ajvr.24.09.0258

Nagarajan, R., Lyu, J., Kambali, M., Wang, M., Courtney, C. D., Christian-Hinman, C. A., & Rudolph, U. (2024). Genetic Ablation of Dentate Hilar Somatostatin-Positive GABAergic Interneurons is Sufficient to Induce Cognitive Impairment. Molecular Neurobiology, 61(2), 567-580. https://doi.org/10.1007/s12035-023-03586-3

Luscher, B., Maguire, J. L., Rudolph, U., & Sibille, E. (2023). GABAA receptors as targets for treating affective and cognitive symptoms of depression. Trends in Pharmacological Sciences, 44(9), 586-600. https://doi.org/10.1016/j.tips.2023.06.009

Lyu, J., Nagarajan, R., Kambali, M., Wang, M., & Rudolph, U. (2023). Selective inhibition of somatostatin-positive dentate hilar interneurons induces age-related cellular changes and cognitive dysfunction. PNAS Nexus, 2(5), Article pgad134. https://doi.org/10.1093/pnasnexus/pgad134

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