Professor, Comparative Biosciences
Research: Neurobiology of Cognitive Function in Aging and Pathophysiology of Neuropsychiatric Disorders

Additional Campus Affiliations

Head, Comparative Biosciences
Professor, Comparative Biosciences
Affiliate, Carl R. Woese Institute for Genomic Biology

Recent Publications

Kambali, M., Wang, M., Nagarajan, R., Lyu, J., & Rudolph, U. (2026). Lactate restores PGC1α and BDNF expression rescuing cognitive impairments in a mouse model for schizophrenia. Behavioural Brain Research, 505, Article 116111. https://doi.org/10.1016/j.bbr.2026.116111

Lyu, J., Nagarajan, R., Sharmin, D., Mondal, P., Kambali, M., Wang, M., Zhou, J., Inoue, M., Cook, J. M., & Rudolph, U. (2026). Prevention of microglial activation and postoperative cognitive deficits by positive allosteric modulation of α5-GABAA receptors. British Journal of Pharmacology. Advance online publication. https://doi.org/10.1111/bph.70474

Nagarajan, R., Lyu, J., George, J. C., Rudolph, U., & Engin, E. (2026). The role of GABAA receptors in hippocampus-dependent cognitive functions. Neuroscience and Biobehavioral Reviews, 186, Article 106659. https://doi.org/10.1016/j.neubiorev.2026.106659

Fuhr, A., Roediger, R., Simelitidis, M., Gamper-Tsigaras, J., Templin, M., Kormann, M., Antkowiak, B., Rudolph, U., Köhler, D., Rosenberger, P., Ngamsri, K. C., & Konrad, F. M. (2025). Regulation of neutrophil migration in acute pulmonary inflammation by extraneuronal α1 gamma-aminobutyric acidA receptors. Cell Death and Disease, 16(1), Article 313. https://doi.org/10.1038/s41419-025-07488-1

Kambali, M., Li, Y., Unichenko, P., Feria Pliego, J. A., Yadav, R., Liu, J., McGuinness, P., Cobb, J. G., Wang, M., Nagarajan, R., Lyu, J., Vongsouthi, V., Jackson, C. J., Engin, E., Coyle, J. T., Shin, J., Hodgson, N. W., Hensch, T. K., Talkowski, M. E., ... Rudolph, U. (2025). An increased copy number of glycine decarboxylase (GLDC) associated with psychosis reduces extracellular glycine and impairs NMDA receptor function. Molecular Psychiatry, 30(3), 927-942. Article 6388. https://doi.org/10.1038/s41380-024-02711-5

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