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Erin O'Leary

Profile picture for Erin O'Leary

Contact Information

VetMed BSB 3834
Advisor – Paul Bonthuis

Research Interests

Member of the Bonthuis Lab

Research Description

My research focuses on an epigenetic phenomenon known as noncanonical genomic imprinting. Specifically, I investigate this specialized form of parental allele inheritance in the monoamine neurotransmitter system. Of particular interest are the genes which encode for the production of dopamine and serotonin. Tyrosine hydroxylase (Th) regulates production of l-dopa, and Dopa decarboxylase (Ddc) regulates production of dopamine and serotonin. Previous research has found that these genes are biased to express their maternal allele in certain regions of the brain such as the hypothalamus. This brain region, as well as, monoamine neurotransmitters, are highly implicated in regulation of social behavior. My research explores the effects of Ddc and Th imprinting on rodent social behavior. These behaviors range from aggression and dominance to parental and sexual behavior. 

Education

B.A. in Neuroscience from The College of Wooster, Ohio 2018