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Human Head on a computer screeThe Control & Network Connectivity Team (CONNECT lab) studies the connectivity and cognitive functions of large-scale brain networks. Our lab is most interested in networks involved in cognitive control functions such as alertness and attention (cognitive control networks). Distant brain regions are in constant communication with each other. This communication, also called functional connectivity, is foundational to all cognition. Functional connectivity is spatially organized into many large brain networks, but how this network organization is maintained and modulated in the service of flexible cognition is poorly understood. 

One research line of the lab seeks to delineate the function of different cognitive control networks. This research investigates how cognitive control networks modulate processes in “lower-order” brain areas such as perception in sensory cortices.

Another research line focuses on the functional role of intrinsic (spontaneous) network activity. Neural activity and communication across brain networks are continuously ongoing independent of external stimuli or tasks. The CONNECT lab’s research aims at understanding why this intrinsic activity and functional connectivity exists and how it affects behavior.

The CONNECT lab combines various techniques to address these questions in the human brain including functional magnetic resonance imaging (fMRI), electroencephalography (EEG), simultaneous EEG-fMRI and genetic analyses in healthy participants and neurological patients.

Our Principal Investigator is Sepideh Sadaghiani.

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