Additional Campus Affiliations
Professor, Molecular and Integrative Physiology
Head, Molecular and Integrative Physiology
Recent Publications
Kumar, P., Wang, Y., Zhang, Z., Zhao, Z., Cymes, G. D., Tajkhorshid, E., & Grosman, C. (2020). Cryo-EM structures of a lipid-sensitive pentameric ligand-gated ion channel embedded in a phosphatidylcholine-only bilayer. Proceedings of the National Academy of Sciences of the United States of America, 117(3), 1788-1798. https://doi.org/10.1073/pnas.1906823117
Harpole, T. J., & Grosman, C. (2019). A Crucial Role for Side-Chain Conformation in the Versatile Charge Selectivity of Cys-Loop Receptors. Biophysical journal, 116(9), 1667-1681. https://doi.org/10.1016/j.bpj.2019.03.022
Gonzalez-Gutierrez, G., Wang, Y., Cymes, G. D., Tajkhorshid, E., & Grosman, C. (2017). Chasing the open-state structure of pentameric ligand-gated ion channels. Journal of General Physiology, 149(12), 1119-1138. https://doi.org/10.1085/jgp.201711803
Cymesa, G. D., & Grosman, C. (2016). Identifying the elusive link between amino acid sequence and charge selectivity in pentameric ligand-gated ion channels. Proceedings of the National Academy of Sciences of the United States of America, 113(45), E7106-E7115. https://doi.org/10.1073/pnas.1608519113
Cymes, G. D., & Grosman, C. (2015). Engineered Ionizable Side Chains. Advances in experimental medicine and biology, 869, 5-23. https://doi.org/10.1007/978-1-4939-2845-3_2