
Contact Information
1201 W Gregory Drive
Rm 220A
Research Areas
Research Interests
Prenatal immune determinants of neurodevelopment and behavior
Research Description
Dr. Antonson uses translational animal models to investigate inflammatory and neurodevelopmental origins of behavioral abnormalities and mental health disorders. Focusing on the prenatal period as a critical developmental window, Dr. Antonson has demonstrated that maternal insults such as viral infection and psychological stress during pregnancy alter neuroimmune signatures in the offspring brain, leading to disrupted behaviors. Her central research focus is investigating exogenous and endogenous signals, deriving from prenatal maternal immune activation, that shift the function of fetal microglial cells, the resident brain macrophage, and subsequently disrupt microglial-mediated neurodevelopment. Her work also hypothesizes that downstream perturbations of the maternal microbiome propagates detrimental inflammatory signaling that contributes to disruptions in immune balance at the maternal-fetal interface.
Education
Postdoctoral Fellow (2018-2021) Institute for Behavioral Medicine Research, The Ohio State University, Columbus OH
PhD (2013-2018) Immunophysiology and Behavior, University of Illinois Urbana-Champaign, Urbana IL
BS (2009-2013) Biology, Ithaca College, Ithaca NY
Additional Campus Affiliations
Microbial Systems Initiative
Carl R. Woese Institute for Genomic Biology, Environmental Impact on Reproductive Health (EIRH) Research Theme
Interdisciplinary Environmental Toxicology Program (IETP)