Janice Juraska


509 Psychology
Office: 217-333-8546

Mail to:
Department of Psychology
603 E Daniel St
Champaign, IL 61820
Lab Page

Janice Juraska

Professor, Department of Psychology
B.A., Lawrence University
M.A., University of Illinois
Ph.D., University of Colorado

Development and plasticity of the cortex

My students and I examine hormonal and environmental influences on neuronal structure in the cerebral cortex and other areas of the rat nervous system that involve cognition in the rat. Our current emphasis is on two time periods: early development and adolescence/puberty. We have found that adolescence is a time of considerable neuron reorganization including neuronal death, and the hormones secreted during puberty are influencing some of the changes. Current projects include the neural effects of endocrine disruptors (BPA, phthalates) on both neural development and adolescence and the effects of puberty on the neuroanatomical structure of the medial prefrontal cortex and associated behavior.

Collaborative Projects

Children's Center with Sue Schantz

Research Areas

Representative Publications

Kougias D.G., Cortes L.R., Moody L., Rhoads S., Pan Y.X., Juraska J.M. Effects of perinatal exposure to phthalates and a high-fat diet on maternal behavior and pup development and social play. Endocrinology. 159(2): 1088-1105, 2018. PMID: 29300916

Hankosky, ER, Westbrook SR, Haake RM, Willing J, Raetzman LT, Juraska, JM, Gulley JM Age- and sex-dependent effects of methamphetamine on cognitive flexibility and 5-HT2C receptor localization in the orbitofrontal cortex of Sprague-Dawley rats. Behav Brain Res 349:16–24, 2018. PMID: 29715538

Hankosky, E. R., Sherrill, L. K. Ruvola, L. A., Haake, R. M., Kim, T., Hammerslag, L. R., Kougias, D. G., Juraska, J. M., Gulley, J. M. Effects of ?-hydroxy-?-methyl butyrate (HMB) on working memory and cognitive flexibility in an animal model of aging. Nutritional Neuroscience, 20: 379-387, 2017. PMID: 26896292

Juraska J.M., Willing J. Pubertal onset as a critical transition for neural development and cognition. Brain Research, 1654: 87-94, 2017. PMID: 27060769

Kougias, D.G., Hankosky, E.R., Gulley, J.M., Juraska, J. M. Beta-hydroxy-beta-methylbutyrate (HMB) ameliorates age-related deficits in water maze performance, especially in male rats. Physiology & Behavior, 170: 93-99, 2017. PMID: 28038406

Willing J., Cortes L.R., Brodsky J.M., Kim T., Juraska, J.M. Innervation of the medial prefrontal cortex by tyrosine hydroxylase immunoreactive fibers during adolescence in male and female rats. Developmental Psychobiology, 59(5):583-589, 2017. PMID: 28561889

Willing J., Drzewiecki C.M., Cuenod B.A., Cortes L.R., Juraska J.M. A role for puberty in water maze performance in male and female rats. Behavioral Neuroscience, 130(4):422-7, 2016.

Drzewiecki C.M., Willing J., Juraska J.M. Synaptic number changes in the medial prefrontal cortex across adolescence in male and female rats: A role for pubertal onset. Synapse, 70(9):361-8, 2016.

Wise L. M., Sadowski R. N., Kim T., Willing J., Juraska J. M. Long-term effects of adolescent exposure to Bisphenol A on neuron and glia number in the rat prefrontal cortex: Differences between the sexes and cell type. Neurotoxicology, 53: 186-192, 2016.

Kougias, D. G. Nolan, S. O., Koss, W. A., Kim, T., Hankosky E. R., Gulley, J. M., Juraska, J. M. Beta-hydroxy-beta-methylbutyrate (HMB) ameliorates aging effects in the dendritic tree of pyramidal neurons in the medial prefrontal cortex of both male and female rats. Neurobiology of Aging, 40: 78-85, 2016.

Willing J. and J. M. Juraska The timing of neuronal loss across adolescence in the medial prefrontal cortex of male and female rats. Neuroscience, 301:268-275, 2015.

Juraska, J.M. and L.M. Wise Brain: Response to Enrichment. In: James D. Wright (editor-in-chief), International Encyclopedia of the Social & Behavioral Sciences, 2nd edition, Vol 2. Oxford: Elsevier. pp. 835–840, 2015.

Koss, W.A., M.M. Lloyd, R.N. Sadowski, L.M. Wise and J.M. Juraska Gonadectomy before puberty increases the number of neurons and glia in the medial prefrontal cortex of female, but not male, rats. Developmental Psychobiology, 57(3):305-12, 2015.