smmatt2@illinois.edu

1201 W Gregory Drive
Edward R Madigan Lab, Rm 250
Urbana, IL 61801

Lab Page
Publications

Stephanie Matt

Regulation of neuroinflammation in aging through epigenetic mechansims

Research focuses on how aging results in exaggerated neuroinflammation through understanding epigenetic programming of microglia in mice. Specifically, changes in DNA methylation of proinflammatory cytokines are being explored.

Research Areas

Representative Publications

Matt, S. M., Lawson, M.L., & Johnson, R. W. (2016). Aging and peripheral lipopolysaccharide can modulate epigenetic regulators and decrease IL-1b promoter DNA methylation in microglia. Submitted for publication.

Matt, S. M., & Johnson, R. W. (2015). Neuro-immune dysfunction during brain aging: new insights in microglial cell regulation. Curr Opin Pharmacol, 26, 96-101. doi:10.1016/j.coph.2015.10.009

Matt, S., Roth, E. D., & Roth, T. L. (2014). Chapter 5 - Role of Epigenetics in the Brain. In J. P. R. G. Avramopoulos (Ed.), Epigenetics in Psychiatry (pp. 79-99). Boston: Academic Press.

Roth, T. L., Matt, S., Chen, K., & Blaze, J. (2014). Bdnf DNA methylation modifications in the hippocampus and amygdala of male and female rats exposed to different caregiving environments outside the homecage. Dev Psychobiol, n/a-n/a. doi:10.1002/dev.21218

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