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Galvez, Roberto
Assistant Professor, Department of Psychology
Research Interests/ Laboratory Focus
It is a widely accepted fact that the neocortex is a likely site of storage for most memories; however, the process for storage and subsequent retrieval of learned information in the neocortex still eludes us. I am interested in understanding this process; how does the neocortex store and retrieve information. My laboratory will utilize forebrain dependent behavioral paradigms in conjunction with anatomical, molecular and electrophysiological techniques in rodents to characterize learning induced neocortical plasticity not only in young , but also characterize how this plasticity and the underlying mechanism necessary for inducing the plasticity is altered with age and in rodent models of various neurological disorders.
Representative Publications
Galvez, R., Weiss, C., Cua, S., Disterhoft, J., A novel method for precisely timed stimulation of mouse whiskers in a freely moving preparation; application for delivery of the conditioned stimulus in trace eyeblink conditioning. J Neurosci. Methods. 177 p. 434-439 (2009).
Galvez, R., Weiss, C., Cua, S., Disterhoft, J., A novel method for precisely timed stimulation of mouse whiskers in a freely moving preparation; application for delivery of the conditioned stimulus in trace eyeblink conditioning. J Neurosci. Methods. 177 p. 434-439 (2009).
Galvez, R., Weible, A., Disterhoft, J., Cortical barrel lesions impair whisker-CS trace eyeblink conditioning. Learning & Memory. 14 p.84-93 (2007).
Weiss, C., Weible, A.P., Galvez, R. and Disterhoft, J.F., Forebrain-Cerebellar Interactions During Learning. Cell science Reviews. 3 p.200-230 ( 2006).
Galvez, R., Weiss, C., Weible, A., Disterhoft, J., Vibrissa-signaled eyeblink conditioning induces somatosensory cortical plasticity. J Neurosci. 26 p.6062-8 (2006).
Galvez, R. and Greenough, W.T. Sequence of abnormal dendritic spine development in primary somatosensory cortex of a mouse model of the fragile X mental retardation syndrome. Am J Med Genet A., June 1(135) p.155-160 (2005).
Galvez, R., Smith, R.L., Greenough, W.T. Olfactory bulb mitral cell dendritic pruning abnormalities in a mouse model of the fragile X mental retardation syndrome. Dev Brain Res, June 30(157) p.214-216 (2005).
Irwin, S.A., Christmon, C.A., Grossman, A.W., Galvez, R., Kim, S.H., DeGrush, B.J., Weiler, I.J., and Greenough, W.T. Fragile X mental retardation protein levels increase following complex environment exposure in rat brain regions undergoing active synaptogenesis. Neurobiology of Learning and Memory, 83(3) p.180-187 (2005)
Galvez, R., Gopal, A., Greenough, W.T. Somatosensory cortical barrel dendritic abnormalities in a mouse model of the fragile X mental retardation. Brain Res, 971(1) p.83-89 (2003).
Related Research (By Area):
Cell Signaling and Communication
Neurological and Psychiatric Conditions
Aging
Development
Learning, Memory, and Plasticity
Cognitive Neuroscience
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